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Multiple Choice

In the liver, what toxic byproduct of amino acid metabolism is converted to a harmless molecule for removal?

Amino groups removed from amino acids produce ammonia, which is highly toxic to cells. In the liver, ammonia enters the urea cycle and is converted into urea, a much less toxic, water-soluble molecule that can be safely excreted in urine. This detoxification prevents ammonia buildup that would disrupt nervous system function. So the toxic byproduct being converted is ammonia. Bilirubin and glucose are not involved in this detox pathway, and they don’t represent the toxic byproduct produced during amino acid metabolism.

Amino groups removed from amino acids produce ammonia, which is highly toxic to cells. In the liver, ammonia enters the urea cycle and is converted into urea, a much less toxic, water-soluble molecule that can be safely excreted in urine. This detoxification prevents ammonia buildup that would disrupt nervous system function. So the toxic byproduct being converted is ammonia. Bilirubin and glucose are not involved in this detox pathway, and they don’t represent the toxic byproduct produced during amino acid metabolism.