Peyer's patches are located in which tissue?

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Multiple Choice

Peyer's patches are located in which tissue?

They demonstrate how the immune system surveys the gut by locating organized lymphoid tissue within the intestinal mucosa. Peyer's patches are collections of lymphoid follicles that sit in the wall of the small intestine—primarily in the ileum—within the mucosa (and sometimes extending into the submucosa) just beneath the epithelium. This placement is essential because the overlying epithelium contains M cells that sample luminal antigens and deliver them to underlying immune cells, helping to initiate mucosal immunity and IgA production. They are not located in the respiratory tract, esophageal lining, or skin, which is why those tissues don’t contain Peyer's patches.

They demonstrate how the immune system surveys the gut by locating organized lymphoid tissue within the intestinal mucosa. Peyer's patches are collections of lymphoid follicles that sit in the wall of the small intestine—primarily in the ileum—within the mucosa (and sometimes extending into the submucosa) just beneath the epithelium. This placement is essential because the overlying epithelium contains M cells that sample luminal antigens and deliver them to underlying immune cells, helping to initiate mucosal immunity and IgA production. They are not located in the respiratory tract, esophageal lining, or skin, which is why those tissues don’t contain Peyer's patches.

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