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Multiple Choice

What are the two pairs of polypeptide chains of a Y-shaped antibody molecule called?

Antibodies are built from two identical heavy chains and two identical light chains, linked by disulfide bonds to form the classic Y shape. The heavy and light chains come together to create the antigen-binding sites at the tips of the arms and give the molecule its structure. This is why the correct description is heavy chains and light chains—the two distinct types that pair to make a complete antibody. The other terms refer to different proteins (T-cell receptor chains) or to light-chain subclasses, not the two paired types that make up an antibody molecule.

Antibodies are built from two identical heavy chains and two identical light chains, linked by disulfide bonds to form the classic Y shape. The heavy and light chains come together to create the antigen-binding sites at the tips of the arms and give the molecule its structure. This is why the correct description is heavy chains and light chains—the two distinct types that pair to make a complete antibody. The other terms refer to different proteins (T-cell receptor chains) or to light-chain subclasses, not the two paired types that make up an antibody molecule.