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Multiple Choice

What is necrosis?

Necrosis is the tissue destruction that occurs after cells have been injured or destroyed. When cells suffer severe damage, their membranes lose integrity and contents leak out, triggering inflammation in the surrounding tissue. This is an uncontrolled process, unlike programmed cell death (apoptosis), which is orderly and noninflammatory. It’s not simply aging-related cell death, and while healing after necrosis can involve scar formation, the necrotic event itself is the destructive injury rather than the scar tissue that forms later.

Necrosis is the tissue destruction that occurs after cells have been injured or destroyed. When cells suffer severe damage, their membranes lose integrity and contents leak out, triggering inflammation in the surrounding tissue. This is an uncontrolled process, unlike programmed cell death (apoptosis), which is orderly and noninflammatory. It’s not simply aging-related cell death, and while healing after necrosis can involve scar formation, the necrotic event itself is the destructive injury rather than the scar tissue that forms later.