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Multiple Choice

What is the function of regulatory T cells?

Regulatory T cells act as the immune system’s brakes. They keep immune responses in check to prevent damage to self and maintain tolerance. They mainly exert control by secreting suppressive cytokines like IL-10 and TGF-β and through cell-contact mechanisms (such as CTLA-4) that blunt the activation and proliferation of other T cells and can also limit B cell activity. Because their role is to moderate rather than boost responses, they are not driving rapid T cell activation, they don’t enhance antibody production, and they don’t directly kill infected cells (that’s the job of cytotoxic T cells and NK cells). This suppressive, regulatory function is why this option is the best answer.

Regulatory T cells act as the immune system’s brakes. They keep immune responses in check to prevent damage to self and maintain tolerance. They mainly exert control by secreting suppressive cytokines like IL-10 and TGF-β and through cell-contact mechanisms (such as CTLA-4) that blunt the activation and proliferation of other T cells and can also limit B cell activity. Because their role is to moderate rather than boost responses, they are not driving rapid T cell activation, they don’t enhance antibody production, and they don’t directly kill infected cells (that’s the job of cytotoxic T cells and NK cells). This suppressive, regulatory function is why this option is the best answer.