Which cells have CD8 markers and which MHC class do they recognize?

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Multiple Choice

Which cells have CD8 markers and which MHC class do they recognize?

CD8 is the co-receptor used by cytotoxic T cells to recognize antigens presented by MHC class I. MHC I molecules are found on nearly all nucleated cells, and when a cytotoxic T cell detects a peptide on MHC I, it can initiate killing of the infected or abnormal cell. Helper T cells, in contrast, carry CD4 and interact with MHC class II on professional antigen-presenting cells, which is a different pathway. B cells and dendritic cells can present antigens as well, but the defining feature tied to CD8 is the cytotoxic T cell recognizing MHC I. So the cells with CD8 are cytotoxic T cells, and they recognize class I MHC.

CD8 is the co-receptor used by cytotoxic T cells to recognize antigens presented by MHC class I. MHC I molecules are found on nearly all nucleated cells, and when a cytotoxic T cell detects a peptide on MHC I, it can initiate killing of the infected or abnormal cell. Helper T cells, in contrast, carry CD4 and interact with MHC class II on professional antigen-presenting cells, which is a different pathway. B cells and dendritic cells can present antigens as well, but the defining feature tied to CD8 is the cytotoxic T cell recognizing MHC I. So the cells with CD8 are cytotoxic T cells, and they recognize class I MHC.

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