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Multiple Choice

Which enzyme is not involved in pancreatic peptide bond hydrolysis?

The key idea is distinguishing enzymes that cut peptide bonds from those that break carbohydrate bonds. The pancreatic proteases—trypsin, chymotrypsin, and elastase—are all focused on hydrolyzing peptide bonds in dietary proteins; they are secreted by the pancreas (as inactive zymogens) and activated in the small intestine to cleave specific amino acid sequences. Amylase, on the other hand, targets carbohydrates. It hydrolyzes glycosidic bonds in starch, not peptide bonds in proteins. So amylase is not involved in pancreatic peptide bond hydrolysis.

The key idea is distinguishing enzymes that cut peptide bonds from those that break carbohydrate bonds. The pancreatic proteases—trypsin, chymotrypsin, and elastase—are all focused on hydrolyzing peptide bonds in dietary proteins; they are secreted by the pancreas (as inactive zymogens) and activated in the small intestine to cleave specific amino acid sequences.

Amylase, on the other hand, targets carbohydrates. It hydrolyzes glycosidic bonds in starch, not peptide bonds in proteins. So amylase is not involved in pancreatic peptide bond hydrolysis.