Which hormone initiates hunger? Which one induces satiety?

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Multiple Choice

Which hormone initiates hunger? Which one induces satiety?

Hunger and fullness are signaled to the brain by hormones that reflect short-term intake and long-term energy stores. Ghrelin, produced by the stomach, rises before meals to stimulate hunger by acting on hypothalamic circuits (notably promoting orexigenic activity with neuropeptide Y and AgRP). It falls after eating, helping curb the immediate urge to eat. Leptin, released by fat tissue, reflects overall energy stores and acts on the hypothalamus to suppress appetite and promote satiety; higher fat stores raise leptin levels, signaling the brain to eat less, though obesity can involve leptin resistance that blunts this signal. Secretin, another digestive hormone, regulates pancreatic bicarbonate secretion and slows gastric emptying but does not drive hunger or satiety signals. So, the hormone that initiates hunger is ghrelin, and the hormone that induces satiety is leptin.

Hunger and fullness are signaled to the brain by hormones that reflect short-term intake and long-term energy stores. Ghrelin, produced by the stomach, rises before meals to stimulate hunger by acting on hypothalamic circuits (notably promoting orexigenic activity with neuropeptide Y and AgRP). It falls after eating, helping curb the immediate urge to eat. Leptin, released by fat tissue, reflects overall energy stores and acts on the hypothalamus to suppress appetite and promote satiety; higher fat stores raise leptin levels, signaling the brain to eat less, though obesity can involve leptin resistance that blunts this signal. Secretin, another digestive hormone, regulates pancreatic bicarbonate secretion and slows gastric emptying but does not drive hunger or satiety signals.

So, the hormone that initiates hunger is ghrelin, and the hormone that induces satiety is leptin.

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